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0 0.5 1 1.5 2+ Oxygen therapy 79% Improvement Relative Risk c19colchicine.com Avanoglu Guler et al. Colchicine for COVID-19 Prophylaxis Favors colchicine Favors control
Avanoglu Guler, 73 patient colchicine prophylaxis study: 79% lower need for oxygen therapy [p=0.04] https://c19p.org/avanogluguler
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COVID-19 in familial Mediterranean fever: Clinical course and complications related to primary disease
Avanoglu Guler et al., Modern Rheumatology, doi:10.1093/mr/roac074
21 Jul 2022    Source   PDF   Share   Tweet
Retrospective 73 familial Mediterranean fever patients with COVID-19 in Turkey, showing significantly higher risk of hospitalization for respiratory support with non-adherence to colchicine treatment before the infection.
risk of oxygen therapy, 78.8% lower, RR 0.21, p = 0.04, treatment 6 of 66 (9.1%), control 3 of 7 (42.9%), NNT 3.0, inverted to make RR<1 favor treatment, odds ratio converted to relative risk.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Avanoglu Guler et al., 21 Jul 2022, retrospective, Turkey, peer-reviewed, median age 39.5, 14 authors.
Contact: aslihanavanoglu@gmail.com.
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