Brunetti, 66 patient colchicine late treatment PSM study: 73% lower mortality [p=0.03] and 73% higher hospital discharge [p=0.03] https://c19p.org/brunetti
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Colchicine to Weather the Cytokine Storm in Hospitalized Patients with COVID-19
et al., J. Clin. Med., 9:9, 2961, doi:10.3390/jcm9092961
PSM matched analysis from consecutive hospitalized patients, with 33 colchicine and 33 control matched patients, showing lower mortality with treatment.
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risk of death, 72.7% lower, RR 0.27, p = 0.03, treatment 3 of 33 (9.1%), control 11 of 33 (33.3%), NNT 4.1, PSM.
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risk of no hospital discharge, 72.7% lower, RR 0.27, p = 0.03, treatment 3 of 33 (9.1%), control 11 of 33 (33.3%), NNT 4.1, PSM.
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| Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates |
Brunetti et al., 9/14/2020, retrospective, propensity score matching, USA, North America, peer-reviewed, 7 authors.
Late treatment
is less effective
is less effective
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