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Aspirin Molnupiravir
Bamlanivimab Nigella Sativa
Bromhexine Nitazoxanide
Budesonide Povidone-Iod..
Casirivimab/i.. Probiotics
Colchicine Proxalutamide
Conv. Plasma Quercetin
Curcumin Remdesivir
Favipiravir Sotrovimab
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Hydroxychloro.. Vitamin C
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Colchicine study #11 of 12   All Outcomes
7/10 Late treatment study
Gaitán-Duarte et al., medRxiv, doi:10.1101/2021.07.06.21260085 (Preprint)
Effectiveness of Rosuvastatin plus Colchicine, Emtricitabine/Tenofovir and a combination of them in Hospitalized Patients with SARS Covid-19
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RCT 633 hospitalized patients in Colombia, 153 treated with colchicine + rosuvastatin, not showing statistically significant differences in outcomes. Improved results were seen with the combination of emtricitabine/tenofovir disoproxil + rosuvastatin + colchicine. NCT04359095.
Gaitán-Duarte et al., 7/10/2021, Randomized Controlled Trial, Colombia, South America, preprint, 17 authors, this trial uses multiple treatments in the treatment arm (combined with rosuvastatin) - results of individual treatments may vary.
risk of death, 19.0% lower, RR 0.81, p = 0.43, treatment 22 of 153 (14.4%), control 28 of 161 (17.4%), adjusted per study, 28 days.
risk of mechanical ventilation, 15.0% lower, RR 0.85, p = 0.15, treatment 27 of 136 (19.9%), control 27 of 140 (19.3%), adjusted per study.
risk of ICU admission, 1.0% lower, RR 0.99, p = 0.97, treatment 19 of 113 (16.8%), control 18 of 114 (15.8%), adjusted per study.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. For an individual study the most serious outcome may have a smaller number of events and lower statistical signficance, however this provides the strongest evidence for the most serious outcomes when combining the results of many trials.
All 12 studies   All Outcomes
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