RECOVERY trial reports not finding a significant difference with colchicine treatment. Very minimal details are provided but treatment may be very late as with previous RECOVERY results.
Horby et al., 3/5/2021, Double Blind Randomized Controlled Trial, United Kingdom, Uk, preprint, 2 authors.
risk of death, 2.0% higher, RR 1.02, p = 0.63, group sizes not provided.
Effect extraction follows pre-specified rules
prioritizing more serious outcomes. For an individual study the most serious
outcome may have a smaller number of events and lower statistical signficance,
however this provides the strongest evidence for the most serious outcomes
when combining the results of many trials.