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0 0.5 1 1.5 2+ Mortality 68% Improvement Relative Risk c19colchicine.com Hunt et al. Colchicine for COVID-19 EARLY TREATMENT Favors colchicine Favors control
Hunt, 26,508 patient colchicine early treatment study: 68% lower mortality [p=0.003] https://c19p.org/hunto
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Medications Associated with Lower Mortality in a SARS-CoV-2 Positive Cohort of 26,508 Veterans
Hunt et al., Journal of General Internal Medicine, doi:10.1007/s11606-022-07701-3
29 Jun 2022    Source   PDF   Share   Tweet
Retrospective 26,508 consecutive COVID+ veterans in the USA, showing lower mortality with multiple treatments including colchicine. Treatment was defined as drugs administered ≥50% of the time within 2 weeks post-COVID+, and may be a continuation of prophylactic treatment in some cases, and may be early or late treatment in other cases. Further reduction in mortality was seen with combinations of treatments.
risk of death, 68.0% lower, RR 0.32, p = 0.003, treatment 9 of 402 (2.2%), control 1,603 of 26,106 (6.1%), NNT 26, adjusted per study, day 30.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Hunt et al., 6/29/2022, retrospective, USA, peer-reviewed, 8 authors, study period 1 March, 2020 - 10 September, 2020.
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