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0 0.5 1 1.5 2+ Hospitalization -406% Improvement Relative Risk Symptomatic case -73% Case -24% c19colchicine.com Oztas et al. Colchicine for COVID-19 Prophylaxis Favors colchicine Favors control
Oztas, 1,278 patient colchicine prophylaxis study: 406% higher hospitalization [p=0.12], 73% more symptomatic cases [p=0.07], and 24% more cases [p=0.35] https://c19p.org/oztaso
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Frequency and Severity of COVID-19 in Patients with Various Rheumatic Diseases Treated Regularly with Colchicine or Hydroxychloroquine
Oztas et al., Journal of Medical Virology, doi:10.1002/jmv.27731
21 Mar 2022    Source   PDF   Share   Tweet
Retrospective 635 HCQ users and 643 household contacts, showing higher risk with colchicine in unadjusted results.
Patients with conditions leading to the use of colchicine may have significantly different baseline risk, e.g. [Topless].
risk of hospitalization, 406.3% higher, RR 5.06, p = 0.12, treatment 5 of 635 (0.8%), control 1 of 643 (0.2%).
risk of symptomatic case, 72.7% higher, RR 1.73, p = 0.07, treatment 29 of 635 (4.6%), control 17 of 643 (2.6%).
risk of case, 24.4% higher, RR 1.24, p = 0.35, treatment 43 of 635 (6.8%), control 35 of 643 (5.4%).
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
This study is excluded in the after exclusion results of meta analysis: excessive unadjusted differences between groups.
Oztas et al., 3/21/2022, retrospective, Turkey, Europe, peer-reviewed, 15 authors.
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