Retrospective 301 pneumonia patients in Colombia showing lower mortality with colchicine treatment.
Pinzón et al., 10/23/2020, retrospective, Columbia, South America, preprint, 9 authors.
risk of death, 34.5% lower, RR 0.65, p = 0.18, treatment 14 of 145 (9.7%), control 23 of 156 (14.7%), odds ratio converted to relative risk.
Effect extraction follows pre-specified rules
prioritizing more serious outcomes. For an individual study the most serious
outcome may have a smaller number of events and lower statistical signficance,
however this provides the strongest evidence for the most serious outcomes
when combining the results of many trials.