Clinical characteristics and risk factors for mortality of hospitalized patients with COVID-19 in a community hospital: A retrospective cohort study

11/5 Late treatment study

Rodriguez-Nava et al., Mayo Clinic Proceedings: Innovations, Quality & Outcomes (Peer Reviewed)
Clinical characteristics and risk factors for mortality of hospitalized patients with COVID-19 in a community hospital: A retrospective cohort study

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Retrospective 313 patients, mostly critical stage and mostly requiring respiratory support. Confounding by indication likely.

Rodriguez-Nava et al., 11/5/2020, retrospective, USA, North America, peer-reviewed, median age 68.0, 8 authors.

risk of death, 5.5% lower, RR 0.94, p = 0.87, treatment 16 of 52 (30.8%), control 85 of 261 (32.6%), unadjusted.

This study is excluded in meta analysis: substantial unadjusted confounding by indication likely, excessive unadjusted differences between groups, unadjusted results with no group details.

Effect extraction follows pre-specified rules prioritizing more serious outcomes. For an individual study the most serious outcome may have a smaller number of events and lower statistical signficance, however this provides the strongest evidence for the most serious outcomes when combining the results of many trials.

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