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0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Mortality 6% Improvement Relative Risk c19colchicine.com/rodrigueznavao.html Favors colchicine Favors control
5 November 2020 - Late treatment study
Clinical characteristics and risk factors for mortality of hospitalized patients with COVID-19 in a community hospital: A retrospective cohort study
Rodriguez-Nava et al., Mayo Clinic Proceedings: Innovations, Quality & Outcomes (Peer Reviewed)
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Retrospective 313 patients, mostly critical stage and mostly requiring respiratory support. Confounding by indication likely.
risk of death, 5.5% lower, RR 0.94, p = 0.87, treatment 16 of 52 (30.8%), control 85 of 261 (32.6%), NNT 56, unadjusted.
Effect extraction follows pre-specified rules prioritizing more serious outcomes.
This study is excluded in the after exclusion results of meta analysis: substantial unadjusted confounding by indication likely, excessive unadjusted differences between groups, unadjusted results with no group details.
Rodriguez-Nava et al., 11/5/2020, retrospective, USA, North America, peer-reviewed, median age 68.0, 8 authors.
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