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All Studies   Meta Analysis   Recent: 
0 0.5 1 1.5 2+ Mortality 42% Improvement Relative Risk Ventilation 53% Discharge 42% Hospitalization time 5% no CI c19colchicine.com Sandhu et al. Colchicine for COVID-19 LATE TREATMENT Favors colchicine Favors control
Sandhu, 112 patient colchicine late treatment study: 42% lower mortality [p=0.0006], 53% lower ventilation [p<0.0001], 42% higher hospital discharge [p=0.0006], and 5% shorter hospitalization https://c19p.org/sandhu
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A Case Control Study to Evaluate the Impact of Colchicine on Patients Admitted to the Hospital with Moderate to Severe COVID-19 Infection
Sandhu et al., Canadian Journal of Infectious Diseases and Medical Microbiology, doi:10.1155/2020/8865954
27 Oct 2020    Source   PDF   Share   Tweet
Prospective cohort study of hospitalized patients in the USA, 34 treated with colchicine, showing lower mortality and intubation with treatment.
risk of death, 41.7% lower, RR 0.58, p < 0.001, treatment 16 of 34 (47.1%), control 63 of 78 (80.8%), NNT 3.0.
risk of mechanical ventilation, 52.9% lower, RR 0.47, p < 0.001, treatment 16 of 34 (47.1%), control 68 of 68 (100.0%), NNT 1.9.
risk of no hospital discharge, 41.7% lower, RR 0.58, p < 0.001, treatment 16 of 34 (47.1%), control 63 of 78 (80.8%), NNT 3.0.
hospitalization time, 4.5% lower, relative time 0.95, treatment 34, control 78.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Sandhu et al., 10/27/2020, prospective, USA, North America, peer-reviewed, 4 authors.
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Late treatment
is less effective
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