Retrospective 65 ICU patients in the USA and Honduras, showing shorter ICU stay with combined treatment including colchicine,
LMWH, tocilizumab, dexamethasone, and methylprednisolone.
risk of death, 22.8% lower, RR 0.77, p = 0.60, treatment 5 of 35 (14.3%), control 12 of 30 (40.0%), NNT 3.9, adjusted per study, odds ratio converted to relative risk, multivariable.
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ICU time, 39.9% lower, relative time 0.60, p = 0.03, treatment 35, control 30, adjusted per study, multivariable.
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Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
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Valerio Pascua et al., 1/7/2021, retrospective, multiple countries, multiple regions, peer-reviewed, 19 authors, study period 10 June, 2020 - 6 August, 2020, average treatment delay 6.1 days, this trial uses multiple treatments in the treatment arm (combined with LMWH, tocilizumab, dexamethasone, methylprednisolone) - results of individual treatments may vary.